TY - JOUR TI - Insulin Allergy Successfully Managed Using a Combination Of Multi-hexamer-forming Insulin Degludec and Vildagliptin-A case report A1 - , Asim Hassan A2 - Jaja, Bilal A3 - Elamin, Motasim A4 - Sifri, Saud Al A5 - JF - European Journal of Medical Case Reports JO - EJMCR SN - 2520-4998 VL - 3 IS - 2 SP - 87 EP - 90 Y1 - 2019 AB - Background: With the introduction of recombinant formulations insulin allergy is rare, occurring in less than 1% of patients treated with insulin. However, it is a serious situation requiring immediate attention, both due to the hypersensitivity reaction and severe life threatening glucose disequilibrium. Case presentation: A case of a 68-year-old male known diabetic for 35 years noticed some generalized itching, accompanied with maculopapular, mixed vasculitic and bullous lesions. Humalog Mix50/50 was stopped and patient was started on different combinations but to no avail. Before insulin desensitization a trial of degludec was given. Fortunately, the patient tolerated degludec and vildagliptin, and sugars came under control.Conclusion: This combination of multi-hexamer-forming ultra-long-acting insulin plus a DPP4 inhibitor vildagliptin could be an effective combination in controlling blood sugars in patients who have severe allergy to multiple drugs including oral hypoglycemic agents and various insulin preparations. PB - https://www.ejmcr.com DO - 10.24911/ejmcr/173-1553374788 UR - https://www.ejmcr.com/?mno=38944 ER -