TY - JOUR TI - Approach to alloimmune thrombocytopenia: case report A1 - Alabdulqader, Njood A A2 - AlAmri, Raghdah A A3 - AlShammari, Razan Z A4 - Alarfaj, Abdulrahman A A5 - Alqahtani, Nourah H JF - International Journal of Medicine in Developing Countries JO - IJMDC SN - 1658-7820 VL - 6 IS - 2 SP - 411 EP - 414 Y1 - 2022 AB - Background: Fetomaternal alloimmune thrombocytopenia (FMAIT) is a rare disease that occurs when the mother’s immune system produces antibodies against foreign platelet antigens, which are inherited from the father, in the foetus. These antibodies can cross the placental barrier and opsonized fetal platelets, causing fetal thrombocytopenia and increasing the risk of bleeding.Case Presentation: In this study, the case of a 32-year-old female was presented with an affected first pregnancybwith FMAIT followed by surviving and healthy subsequent pregnancies. After the diagnosis of alloimmune thrombocytopenia was established in the first pregnancy, the management plan for the subsequent pregnancies was maternal administration of IVIG 1 g/kg/week, with the addition of hydrocortisone 0.5 mg/kg/ week from 20 weeks age of gestation until the fetal delivery.Conclusion: FMAIT is one of the most common causes of antenatal fetal bleeding. Timely management is the best way to preserve pregnancy. Effective prophylaxis in antenatal care with IVIG infusion and corticosteroids has been reported. However, no mainstay mode of delivery has been agreed upon until now. PB - https://www.ijmdc.com DO - 10.24911/IJMDC.51-1639250090 UR - https://www.ijmdc.com/?mno=48433 ER -