TY - JOUR TI - Typhoid fever with hemophagocytic lymphohistiocytosis masquerading as dengue fever: a case report A1 - Yin, Wong Ji A2 - Wei, Poh Kok A3 - Shean, Wong Poh A4 - Hafidzah, Nik A5 - Suryani, Sharifah A6 - Ken, Cheah Chee A7 - Koi, Ng Tiang JF - European Journal of Medical Case Reports JO - EJMCR SN - 2520-4998 VL - 4 IS - 2 SP - 75 EP - 78 Y1 - 2020 AB - Background: Dengue fever classically presents with fever, arthralgia, myalgia, leukopenia, and thrombocytopenia. A classical presentation with a positive serology test is usually enough to make the diagnosis in an endemic area.Case Presentation: A 30-year-old man presented with fever, leucopenia, thrombocytopenia, hepatitis, and delirium. Dengue Immunoglobulin M (IgM) serology was positive. Blood culture grew Salmonella typhi, his ferritin was raised, and bone marrow histology showed histiocytes and hemophagocytic activity. A 2-week course of ceftriaxone (60-75 mg/kg/day) and intravenous immunoglobulin (0.4 g/kg once a day) for 3 days resulted in complete resolution of his illness.Conclusion: We report a case of typhoid fever with hemophagocytic lymphohistiocytosis mimicking as dengue fever due to cytopenias and hepatitis, and dengue IgM serology was positive. Although rare, a high index of suspicion is required for early diagnosis and treatment. PB - https://www.ejmcr.com DO - 10.24911/ejmcr/173-1574044842 UR - https://www.ejmcr.com/?mno=74101 ER -